. Markets and Services
. Latest news
Ovotransferrin Hydrochloride
(Iron Binding Protein)
OVT
Ovotransferrin is a neutral glycoprotein synthesized in the hen oviduct and deposited in the albumen fraction of eggs at a ratio of 12% of the total protein content. It binds transition metals (Fe[III], Cu[III], Al[III]) very tightly and specifically with binding log constant of about 15 at pH 7.0 and above. Ovotransferrin is a covalent dimer protein, composed of a N- and a C-terminal domain, each one binding one atom-ion of transition metal. The C-terminal domain is glycosylated on Asn-473. Ovotransferrin from Belovo is a white free flowing lyophilised powder, free of any visible impurities.
Ovotransferrin can be used as a nutritional ingredient in iron-fortified products such as iron supplements, iron fortified mixes for instant drinks, sport bars and protein supplements and iron-fortified beverages.
There is also extensive evidence of an antibacterial effect of ovotransferrin based on iron deprivation, iron being an essential growth factor for most micro-organisms. In vivo, ovotransferrin demonstrates therapeutic properties against acute enteritis in infants (Corda, R., Biddau, P., Corrias, A., and Puxeddu, E. (1983) 'Conalbumin in the treatment of acute enteritis in the infant', Int. J. Tiss. Reac. V(1), 117-123 ).
